Perampanel (PER)
1) The main possible mechanism: a non-competitive antagonist of the ionotropic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor on post-synaptic neurons.
2) Therapeutic indications: Relatively broad-spectrum antiepileptic drugs have a certain effect on various types of seizures.
3) Warning: Considering that this product contains lactose, people with lactose intolerance should avoid using it.
4) Dosage for children: Click to view the dosage for children of different ages and weights.
5) Major adverse reactions in children: Some patients will have dizziness and drowsiness after use. In addition, some patients will be irritable and gain weight after use.
6) Interaction with other anti-epileptic drugs: Carbamazepine, oxcarbazepine and phenytoin sodium can reduce the blood concentration of this drug.
7) Interaction with non-anti-epileptic drugs: Taking alcohol at the same time may increase the inhibitory effect on the central nervous system.