English 
简体中文 Vigabatrin (VGB)
1) The main possible mechanism: an irreversible inhibitor of γ-aminobutyric acid transaminase (GABA-T), which can increase the level of GABA in the central nervous system.
2) Therapeutic indications: It is mainly suitable for the treatment of infantile spasms, especially for infantile spasms caused by tuberous sclerosis.
3) Warning: In addition to infantile spasm, it is rarely selected for other types of epilepsy. In addition, it may aggravate the absence seizures.
4) Dosage for children: Click to view the dosage for children of different ages and weights.
5) Major adverse reactions in children: The possible visual field defect is the main adverse reaction. Some may have drowsiness, dizziness, ataxia, weight gain, tremor, etc. In addition, some children may show excitement and anxiety.
6) Interaction with other anti-epileptic drugs: It can reduce the concentration of phenytoin sodium and may increase the peak concentration of clonazepam.
7) Interaction with non-anti-epileptic drugs: Not yet clear.